Melotears (manufactured by Indiana Ophthalmics) is an over-the-counter artificial tear and ocular lubricant eye drop formulation designed to moisten, protect, and soothe dry or irritated eyes.
Active Ingredient & Mechanism of Action
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Active Ingredient: Hypromellose (Hydroxypropyl Methylcellulose) 0.3% w/v.
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Mechanism: Hypromellose is a hydrophilic visco-elastic polymer that acts as a synthetic substitute for natural tears. It binds to water on the ocular surface, stabilizing the tear film and creating a protective, lubricating layer across the cornea and conjunctiva to prevent rapid tear evaporation.
Key Clinical Indications
Melotears is used for the temporary relief of:
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Dry Eye Syndrome: Dryness and burning resulting from reduced natural tear production (keratoconjunctivitis sicca).
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Digital Eye Strain: Fatigue, grittiness, or dryness caused by prolonged computer, phone, or TV screen use (which reduces normal blink rate).
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Environmental Irritation: Eye discomfort triggered by air conditioning, wind, smoke, dust, or dry heating environments.
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Hard Contact Lens Discomfort: Soothing ocular surface friction (though specific lens removal rules apply).
Administration & Dosage Guidelines
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Standard Dosing: Instill 1 to 2 drops into the affected eye(s) 3 to 4 times daily as needed, or as recommended by an eye care professional.
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Application Steps:
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Wash hands thoroughly before opening the bottle.
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Tilt head back, pull down the lower eyelid to create a small pocket, and squeeze 1 drop inside.
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Avoid touching the dropper tip to your eye, eyelid, or fingers to keep the solution sterile.
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Close your eyes gently for 1 to 2 minutes after instillation.
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Safety Precautions & Important Warnings
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Contact Lens Safety: Melotears contains Benzalkonium Chloride as a preservative. Soft contact lenses can absorb this preservative, potentially causing corneal irritation or discoloration of the lenses.
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Rule: Remove soft contact lenses before applying drops and wait at least 15 minutes before reinserting them.
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28-Day Discard Rule: Discard the bottle 4 weeks (28 days) after opening, even if solution remains, to prevent bacterial contamination.
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Temporary Vision Blurring: Expect mild, transient blurring of vision immediately following application. Do not drive or operate machinery until vision becomes completely clear.
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When to Seek Care: Discontinue use and consult a physician if you experience eye pain, persistent redness, vision changes, or if dry eye symptoms persist beyond 72 hours.











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